"This is and continues to be the role of a lifetime and an adventure of utter utter joy", she said during her acceptance speech.
The Emmy statuette depicts a winged woman, and this year's Emmy telecast celebrated a TV season in which women, as never before, were able to soar.
And what would be a bigger thank you to Hulu while hurting all of CBS and Hulu's other competitors than finding a way to give one of their most popular shows an upset Emmy win?
Not long after Laura Dern, the "Big Little Lies" actress who's been working since she was 11 years old, admitted to working "with maybe 12 women" throughout her decades-long career, her colleagues Witherspoon and Kidman declared 2017 "an incredible year for women on television".
Alec Baldwin accepting his award for Saturday Night Live.
"Veep" could also be a repeat victor for best comedy series, with actor-director Donald Glover's hip-hop themed "Atlanta" and contemporary African-American family show "black-ish" seen by pundits as its closest rivals.
"Not since "Mad Men" began its. winning streak in 2008 has there been such a wide open field for the night's most prestigious trophy: best drama series", said weekly trade paper Variety.
That strategy has paid off not only in terms of subscribers, but also industry recognition, like the Emmy awards. Netflix had three dramas nominated on Sunday - "The Crown", "House of Cards" and "Stranger Things" - but "The Handmaid's Tale" won acclaim from Emmy voters.
When the Emmy nominations came out in July, there was significant heartbreak: The Leftovers, BoJack Horseman, Insecure, Ted Danson from The Good Place, and Michael McKean from Better Call Saul were all nowhere to be seen.
Then there was host Stephen Colbert's string of one-liners about the man he considered the biggest television star of the past year, and former White House press secretary Sean Spicer's jaw-dropping cameo in Colbert's opening monologue.
"This will be the largest audience to witness an Emmys, period".
"Wow", Colbert replied. "That really soothes my fragile ego".
Later in the show, Dern and Skarsgård's castmate, Kidman, won best movie or limited-series drama actress.
It is the actress' first Emmy win. So now, more great roles for women, please.
She thanked the show for shining "a light on domestic abuse".
Supporting Actress, Comedy Series: Kate McKinnon, "Saturday Night Live". It was the third win in a row for the series.
The actress played presidential candidate Hillary Clinton during the most recent season, and thanked Clinton during her acceptance speech.
Supporting Actress, Drama Series: Ann Dowd, "The Handmaid's Tale". Lithgow won for his role on the Netflix series "The Crown". It also won outstanding limited series. At one point, Colbert said that Trump never got over not winning an Emmy for his reality show The Apprentice, stating, "Unlike the presidency, Emmys go to the victor of the popular vote".