Drawing a comparison between Donald Trump and the boss from "9 to 5", the women assert that "we refuse to be controlled by a sexist, egotistical, lying, hypocritical bigot". In a way you can say the Handmaids have escaped.
"I remember the first time we won this award", the series creator Lorne Michaels said on the stage. Nicole Kidman took home Outstanding Actress prize and her co-stars Laura Dern and Alexander Skarsgard also won big.
And then The Handmaid's Tale capped its run with its fifth win of the night and eighth overall for Outstanding Drama Series.
Stranger Things' Millie Bobby Brown, 13, missed out on becoming the youngest ever Emmy victor at the Microsoft Theatre when the Briton was beaten to best supporting actress in a drama series by Ann Dowd in The Handmaid's Tale. "And my mother. You are courageous and strong and smart and you have taught me that you can be kind and a f-ing badass". I think we should go in a new direction.
John Lithgow won the first award of the night, Outstanding Supporting Actor for playing Winston Churchill on The Crown.
She thanked her mom and had to be censored for a part of her tribute, which we can only assume included some swears.
Riz Ahmed won Best Actor in a Limited Series for last summer's The Night Of.
The former White House press secretary made fun of his infamous inauguration crowd speech during the show's opening.
She told reporters backstage that the role had been "the greatest honour of my life" and talked of the "special kind of electricity" on set every week.
Miller spoke onstage after presenter Oprah Winfrey announced Handmaid's Tale as the victor, with the cast and crew - and Atwood, whom he thanked as she "created this world for us all". In the past twenty years, four shows have won the best drama Emmy for their first seasons - "Homeland", "Mad Men", "Lost" and "The West Wing".
Adelaide-born Papandrea has become a powerhouse Hollywood producer with films including Gone Girl, Milk and Wild, but the only significant award nomination she has received was an AFI nomination in 2000 for Better Than Sex.
One of the episodes, San Junipero, also won the trophy for best TV movie.
"Veep" star Julia Louis-Dreyfus wins an unprecedented sixth consecutive Emmy Award for her performance as fictional politician Selina Meyer. With HBO's "Game of Thrones" back in contention next season, we have an exciting battle brewing for next year's ceremony.