Eden Hazard is expected to start the game on the bench, as he continues his return to full fitness in anticipation of seven games in 21 days.
And Antonio Conte has now revealed that Drinkwater may miss the clash with the Azerbaijan side at Stamford Bridge.
Chelsea are at home to Azerbaijan outfit Qarabag and Antonio Conte should be able to make changes to his first team squad with little worry over the win.
"I don't know", he said. A home game against the newcomers Qarabag to kick off their Champions League campaign offers Chelsea the flawless stage to gain some much-needed momentum to mount a genuine challenge in the showpiece event.
The group stage of this year's Champions League kicks off today with Man United and Chelsea in action from England.
While Chelsea are the heavy favourites, will Qarabag cause them some trouble? "We try to win every game". Both had N'Golo Kanté playing for them, which nearly certainly is not.
Despite his caution, Conte will believe that his side can have a deep run in the competition they won in 2012.
After a summer where they have brought in Neymar and Kylian Mbappe they have to go far in the Champions League.
"It is easier now for me and my job at this point of the season".
Chelsea's starting lineup could thus feature several new faces, including veteran goalkeeper Wilfredo Caballero and youngster Charly Musonda Jr.
Qarabag striker Dino Ndlovu scored four goals in six games in this season's Champions League qualifiers. We have quality throughout this squad, but we're looking forward, we're excited by this competition.
Qarabag will likely line up in a 4-1-4-1 formation, with former Birmingham City midfielder Michel in midfield and Dino Ndlovu leading the line. If you want to do this, you risk a lot. A solid return off the bench against Leicester just lacked a goal, in which he will look to get on Tuesday night.
"I'm delighted to be back and available for selection". Chelsea will be keen to start well, given a trip to Atletico Madrid and double header with Roma follow. So, if I have to choose between the two, it would be the Champions League.
A stable financial backing gave them a chance to sign players from overseas with the foreign contingent assisting them to four consecutive national titles since 2014.