Manager Martin O'Neill has been dealt a fresh blow by the news playmaker Wes Hoolahan is out of the Republic of Ireland's World Cup qualifier against Wales.
Hoolahan picked up a serious-looking hamstring injury in Norwich's win over Barnsley on Saturday and Ireland manager Martin O'Neill told the press today that he's likely to be missing for a "number of weeks".
Lawrence will also miss the match due to a groin injury and has been replaced by Liverpool's Harry Wilson.
Injuries to Ciaran Clark, Harry Arter, Paul McShane, Rob Elliot, David McGoldrick and Liam Kelly have ruled them out of the squad.
"The scan came back this morning and it's bad news for us and for his club".
Meanwhile, Newcastle striker Daryl Murphy has remained in the United Kingdom for a scan on a calf problem though James McCarthy has travelled to Dublin to join the squad though he remains a doubt with a hamstring injury.
"James has come over and we'll see how he is". He'll just take it on a day-to-day basis.
But this Wales team are a very strong unit and it looks as though they will have a full-strength squad to choose from for the trip to Dublin with talisman Gareth Bale back to full fitness and form, while other key players like Aaron Ramsey, Joe Allen, Ashley Williams and Wayne Hennessey are all available for selection.
He missed Bournemouth's 2-0 win against Swansea this evening with a thigh injury, and while it had been believed that the midfielder was just suffering from a minor knock, his manager Eddie Howe appears to have ruled him out of featuring in the upcoming global break.
Defenders: Seamus Coleman, Cyrus Christie, Richard Keogh, Alex Pearce, John O'Shea, Andy Boyle, John Egan, Stephen Ward.
News of Daryl Murphy was not so encouraging for the Irish.
"He's been the most improved player in the world over the last couple of years and, as we've seen many times before, he is capable of winning a game with a moment of magic". If he doesn't train [on Tuesday], he'll train on Wednesday, so he'll be okay.